A comparative toxicological evaluation of emerging nicotine analogs 6-methyl nicotine and nicotinamide: a scoping review.
Effah F, Sun Y, Lin K, Rahman I.Arch Toxicol. 2025 Apr;99(4):1333-1340. doi: 10.1007/s00204-025-03960-1. Epub 2025 Feb 12.PMID: 39937258
Chemosensory tobacco product toxicology part 1: sensory mechanisms.
Lin W, Hill T 3rd, Stroup AM, Sarles SE, Ogura T, Augustine F, O’Sullivan S, Rahman I, Robinson R, Jabba SV, Nuss C, Hensel E.Toxicol Sci. 2025 Oct 1;207(2):261-271. doi: 10.1093/toxsci/kfaf090.PMID: 40708233 Free PMC
Dr. Jekyll or Mr. Hyde: The multifaceted roles of miR-145-5p in human health and disease.
Rahman MS, Ghorai S, Panda K, Santiago MJ, Aggarwal S, Wang T, Rahman I, Chinnapaiyan S, Unwalla HJ.Noncoding RNA Res. 2024 Nov 10;11:22-37. doi: 10.1016/j.ncrna.2024.11.001. eCollection 2025 Apr.PMID: 39736851 Free PMC article. Review.
Heterogeneity of Cellular Senescence, Senotyping, and Targeting by Senolytics and Senomorphics in Lung Diseases.
Ozdemir SA, Faizan MI, Kaur G, Shaikh SB, Ul Islam K, Rahman I.Int J Mol Sci. 2025 Oct 4;26(19):9687. doi: 10.3390/ijms26199687.PMID: 41096951 Free PMC article. Review.
Toxicity of humectants propylene glycol and vegetable glycerin in electronic nicotine delivery systems.
Sun Y, Lin K, Effah F, Cartujano Barrera F, Li D, McIntosh S, McGraw MD, Rahman I.Toxicol Lett. 2025 Nov;413:111739. doi: 10.1016/j.toxlet.2025.111739. Epub 2025 Oct 1.PMID: 41043656 Review.
METHODS: Database searches were performed using PubMed for relevant literature published from 1/1/2014-9/1/2025. Cited articles about the prevalence, toxicities, and public perceptions of PG/VG. …
Chemical and physiological interactions between e-liquid constituents: cause for concern?
Strongin RM, Sharma E, Erythropel HC, Kassem NOF, Noël A, Peyton DH, Rahman I.Tob Control. 2025 May 15;34(3):393-396. doi: 10.1136/tc-2023-058546.PMID: 38658055 Free PMC article.
Chemosensory tobacco product toxicology part 2: toxicological testing, assays, and state of the science.
Lin W, Hill T 3rd, Stroup AM, Sarles SE, Ogura T, Augustine F, O’Sullivan S, Rahman I, Robinson R, Jabba SV, Nuss C, Hensel E.Toxicol Sci. 2025 Oct 1;207(2):272-288. doi: 10.1093/toxsci/kfaf091.PMID: 40705669 Free PMC
Childhood Interstitial Lung Disease (chILD) Associated With Toxic Chemical Inhalation Exposures: A State-of-the-Art Review.
Hadley W, Lacagnina R, Rahman I, Casey AMH, Deterding R, Deutsch G, McGraw MD.Pediatr Pulmonol. 2025 Dec;60(12):e71401. doi: 10.1002/ppul.71401.PMID: 41306063 Review.
Caveolin-1 Scaffolding Domain Peptide (CSP7): A Novel Target for Idiopathic Pulmonary Fibrosis.
Shaikh SB, Rahman I.Am J Respir Cell Mol Biol. 2025 Jan;72(1):14-15. doi: 10.1165/rcmb.2024-0314ED.PMID: 39292198 Free PMC article. No abstract available.
An Intrinsic-hoc Framework for Heterogeneous Cellular Senescence Elucidation Using Deep Graph Representation Learning and Experimental Validation.
Ma A, Cheng H, Vanegas NDP, Ghobashi A, Chen H, Rodriguez J, Rosas L, Wang C, Shao J, Jiang Y, Wang X, Rahman I, Lugo-Martinez J, Li D, Pryhuber GS, Bar-Joseph Z, Eickelberg O, Königshoff M, Chung D, Chen R, Finkel T, Mora A, Rojas M, Ma Q.bioRxiv [Preprint]. 2025 Jul 4:2025.07.01.662364. doi: 10.1101/2025.07.01.662364.PMID: 40631080 Free PMC article. Preprint.
Effah F, Sun Y, Lin K, Rahman I A comparative toxicological evaluation of emerging nicotine analogs 6-methyl nicotine and nicotinamide: a scoping review. Arch Toxicol. 2025 Apr;99(4):1333-1340. doi: 10.1007/s00204-025-03960-1. Epub 2025 Feb 12.PMID: 39937258
Strongin RM, Sharma E, Erythropel HC, Kassem NOF, Noël A, Peyton DH, Rahman I.Chemical and physiological interactions between e-liquid constituents: cause for concern?
Tob Control. 2025 May 15;34(3):393-396. doi: 10.1136/tc-2023-058546.PMID: 38658055
Rahman MS, Ghorai S, Panda K, Santiago MJ, Aggarwal S, Wang T, Rahman I, Chinnapaiyan S, Unwalla HJ .Dr. Jekyll or Mr. Hyde: The multifaceted roles of miR-145-5p in human health and disease. Noncoding RNA Res. 2024 Nov 10;11:22-37. doi: 10.1016/j.ncrna.2024.11.001. eCollection 2025 Apr.PMID: 39736851
Lin W, Hill T 3rd, Stroup AM, Sarles SE, Ogura T, Augustine F, O'Sullivan S, Rahman I, Robinson R, Jabba SV, Nuss C, Hensel E. Chemosensory Tobacco Product Toxicology Part 2: Toxicological Testing, Assays, and State of the Science. Toxicol Sci. 2025 Jul 24:kfaf091. doi: 10.1093/toxsci/kfaf091. Online ahead of print.PMID: 40705669
Lin W, Hill T 3rd, Stroup AM, Sarles SE, Ogura T, Augustine F, O'Sullivan S, Rahman I, Robinson R, Jabba SV, Nuss C, Hensel E.Chemosensory Tobacco Product Toxicology Part 1: Sensory Mechanisms. Toxicol Sci. 2025 Jul 24:kfaf090. doi: 10.1093/toxsci/kfaf090. Online ahead of print.PMID: 40708233
Muthumalage T, Sarles E, Wang Q, Hensel E, Hill T 3rd, Rahman I, Robinson R, Stroup AM, Thongphanh K, Miller LA In Vitro assessments of ENDS toxicity in the respiratory tract: Are we there yet? .NAM J. 2025;1:100016. doi: 10.1016/j.namjnl.2025.100016. Epub 2025 Apr 3.PMID: 40264558
Shaikh SB, Balaya RDA, Dagamajalu S, Bhandary YP, Unwalla H, Prasad TSK, Rahman I. A signaling pathway map of plasminogen activator inhibitor-1 (PAI-1/SERPINE-1): a review of an innovative frontier in molecular aging and cellular senescence. Cell Commun Signal. 2024 Nov 14;22(1):544. doi: 10.1186/s12964-024-01910-5. PMID: 39543686; PMCID: PMC11566301.
Kaur G, Sohanur Rahman M, Shaikh S, Panda K, Chinnapaiyan S, Santiago Estevez M, Xia L, Unwalla H, Rahman I. Emerging roles of senolytics/senomorphics in HIV-related co-morbidities. Biochem Pharmacol. 2024 Oct;228:116179. doi: 10.1016/j.bcp.2024.116179. Epub 2024 Mar 29. PMID: 38556028; PMCID: PMC11410549.
handy M, Hill T 3rd, Jimenez-Tellez N, Wu JC, Sarles SE, Hensel E, Wang Q, Rahman I, Conklin DJ. Addressing Cardiovascular Toxicity Risk of Electronic Nicotine Delivery Systems in the Twenty-First Century: "What Are the Tools Needed for the Job?" and "Do We Have Them?". Cardiovasc Toxicol. 2024 May;24(5):435-471. doi: 10.1007/s12012-024-09850-9. Epub 2024 Mar 31. PMID: 38555547.
Kassem NOF, Strongin RM, Stroup AM, Brinkman MC, El-Hellani A, Erythropel HC, Etemadi A, Exil V, Goniewicz ML, Kassem NO, Klupinski TP, Liles S, Muthumalage T, Noël A, Peyton DH, Wang Q, Rahman I, Valerio LG Jr. A review of the toxicity of ingredients in e-cigarettes, including those ingredients having the FDA's "Generally Recognized as Safe (GRAS)" regulatory status for use in food. Nicotine Tob Res. 2024 May 24:ntae123. doi: 10.1093/ntr/ntae123. Epub ahead of print. PMID: 38783714.
Sun Y, Prabhu P, Rahman R, Li D, McIntosh S, Rahman I. e-Cigarette Tobacco Flavors, Public Health, and Toxicity: Narrative Review. Online J Public Health Inform. 2024 May 27;16:e51991. doi: 10.2196/51991. PMID: 38801769; PMCID: PMC11165290.
Sun Y, Prabhu P, Li D, McIntosh S, Rahman I. Vaping: Public Health, Social Media, and Toxicity. Online J Public Health Inform. 2024 Apr 11;16:e53245. doi: 10.2196/53245. PMID: 38602734; PMCID: PMC11046396.
Suryadevara V, Hudgins AD, Rajesh A, Pappalardo A, Karpova A, Dey AK, Hertzel A, Agudelo A, Rocha A, Soygur B, Schilling B, Carver CM, Aguayo-Mazzucato C, Baker DJ, Bernlohr DA, Jurk D, Mangarova DB, Quardokus EM, Enninga EAL, Schmidt EL, Chen F, Duncan FE, Cambuli F, Kaur G, Kuchel GA, Lee G, Daldrup-Link HE, Martini H, Phatnani H, Al-Naggar IM, Rahman I, Nie J, Passos JF, Silverstein JC, Campisi J, Wang J, Iwasaki K, Barbosa K, Metis K, Nernekli K, Niedernhofer LJ, Ding L, Wang L, Adams LC, Ruiyang L, Doolittle ML, Teneche MG, Schafer MJ, Xu M, Hajipour M, Boroumand M, Basisty N, Sloan N, Slavov N, Kuksenko O, Robson P, Gomez PT, Vasilikos P, Adams PD, Carapeto P, Zhu Q, Ramasamy R, Perez-Lorenzo R, Fan R, Dong R, Montgomery RR, Shaikh S, Vickovic S, Yin S, Kang S, Suvakov S, Khosla S, Garovic VD, Menon V, Xu Y, Song Y, Suh Y, Dou Z, Neretti N. SenNet recommendations for detecting senescent cells in different tissues. Nat Rev Mol Cell Biol. 2024 Jun 3. doi: 10.1038/s41580-024-00738-8. Epub ahead of print. PMID: 38831121.
El-Hellani A, Adeniji A, Erythropel HC, Wang Q, Lamb T, Mikheev VB, Rahman I, Stepanov I, Strongin RM, Wagener TL, Brinkman MC. Comparison of emissions across tobacco products: A slippery slope in tobacco control. Tob Induc Dis. 2024 Mar 30;22. doi: 10.18332/tid/183797. PMID: 38560551; PMCID: PMC10980913.
Kassem NOF, Strongin RM, Stroup AM, Brinkman MC, El-Hellani A, Erythropel HC, Etemadi A, Goniewicz ML, Hansen EG, Kassem NO, Li D, Liles S, Noël A, Rezk-Hanna M, Wang Q, Rahman I. Toxicity of waterpipe tobacco smoking: the role of flavors, sweeteners, humectants, and charcoal. Toxicol Sci. 2024 Oct 1;201(2):159-173. doi: 10.1093/toxsci/kfae095. PMID: 39037923; PMCID: PMC11424890.
Shaikh SB, Rahman I. Cav1 Scaffolding Domain Peptide (CSP7): A Novel Target for Idiopathic Pulmonary Fibrosis. Am J Respir Cell Mol Biol. 2024 Sep 18. doi: 10.1165/rcmb.2024-0314ED. Epub ahead of print. PMID: 39292198.
Santiago MJ, Chinnapaiyan S, Panda K, Rahman MS, Ghorai S, Rahman I, Black SM, Liu Y, Unwalla HJ. Altered Host microRNAomics in HIV Infections: Therapeutic Potentials and Limitations. Int J Mol Sci. 2024 Aug 13;25(16):8809. doi: 10.3390/ijms25168809. PMID: 39201495; PMCID: PMC11354509.
Yehao Sun, Chad Newton, PhD, Prital Prabhu, Alannah Dalton, Desjamebra J Robinson, D Min, Dongmei Li, PhD5, Scott McIntosh, PhD and Irfan Rahman, PhD Vaping Greed: Perception, Social Media, and Public Health. JAMA Public Health, 2023
Shaikh, S, C Goracci, A. Tjitpora, Rahman I. Impact of Aging on Immune Function in the Pathogenesis of Chronic Lung Diseases: Potential for Therapeutic Targets" has been successfully submitted online to Expert Review of Respiratory Medicine. 2023
Dongxia Ye, and Rahman I. Emerging oral nicotine products and periodontal diseases” International Journal of Dentistry. 2023
Rahman I and Montuschi P. Insights in Respiratory Pharmacology: Frontiers Pharmacology, 2022
Patty Lee, Philip Blood, Katy Börner, Judith Campisi, Feng Chen, Heike Daldrup-Link, Phil De Jager, Li Ding, Francesca E Duncan, Oliver Eickelberg, Rong Fan, Toren Finkel, Vesna Garovic, Nils Gehlenborg, Carolyn Glass, Ziv Bar-Joseph, Pragati Katiyar, So-Jin Kim, Melanie Königshoff, George Kuchel, Haesung Lee, Jun H Lee, Jian Ma, Qin Ma, Simon Melov, Kay Metis, Ana L Mora, Nicolas Musi, Nicola Neretti, João F. Passos, Irfan Rahman, Juan Carlos Rivera-Mulia, Paul Robson, Mauricio Rojas, Ananda L Roy, Birgit Schilling, Pixu Shi, Jonathan Silverstein, Vidyani Suryadevera, Jichun Xie, Jinhua Wang, An-Kwok Ian Wong, Laura Niedernhofer. Title: NIH SenNet Consortium: Mapping senescent cells in the human body to understand health and disease. Preprints ID: preprints-60034
Sundar I, and Rahman I. Clock in lung diseases: Mechanisms. Trends in Mol Medicine 2022
Sundar I, and Rahman I. Circadian Clock-Based Therapeutics in Chronic Pulmonary Diseases" has been received by journal Trends in Pharmacological Sciences, 2022
Jiries Meehan-Atrash, and Irfan Rahman. A Perspective article:
a. Cannabis vaping: existing and emerging modalities, chemistry, and pulmonary toxicology. ACS: Chemical Research in Toxicology, 2021
Zidian Xie, Irfan Rahman, Maciej L. Goniewicz, Dongmei Li. Perspectives on Epigenetics Alterations Associated with Smoking and Vaping. Function, 2021
Samantha McDonough, Irfan Rahman, and Isaac Sundar. Recent updates on biomarkers of exposure and systemic toxicity in e-cigarette users and EVALI" Am J Physiol. Lung 2020
Gurjot Kaur, Anshuman Gaurav, Thomas Lamb Jr, Melanie Perkins, Thivanka Muthumalage, and Irfan Rahman. Current perspectives on characteristics, composition, and toxicological effects of e-cigarette containing tobacco and menthol/mint flavors. Frontiers in Physiology 2020
Chinnapaiyan S, Dutta RK, Devadoss D, Chand HS, Rahman I, Unwalla HJ. Role of Non-Coding RNAs in Lung Circadian Clock Related Diseases. Int J Mol Sci. 2020 Apr 24;21(8):3013. doi: 10.3390/ijms21083013.
Zahira Quinones Tavarez, Dongmei Li, Daniel P. Croft, Steven R. Gill, Deborah J. Ossip, Irfan Rahman. The Interplay between Respiratory Microbiota and Innate Immunity in the Pathogenesis of Flavor Vaping Induced Lung Dysfunction. Frontier in Microbiology
Hitendra S. Chand, Thivanka Muthumalage, Wasim Maziak, and Irfan Rahman, Perspectives on Pulmonary Toxicity and the Pathophysiology of Electronic Cigarette, or Vaping Product, Use Associated Lung Injury. Frontiers Pharmacol Respir, 2020
Kaur G, Lungarella G, Rahman I. SARS-CoV-2 COVID-19 susceptibility and lung inflammatory storm by smoking and vaping. J Inflamm (Lond). 2020 Jun 10;17:21. doi: 10.1186/s12950-020-00250-8. eCollection 2020.
Robert Tarran, R. Graham Barr, Neal L. Benowitz, Aruni Bhatnagar, Hong W. Chu, Pamela Dalton, Claire M. Doerschuk, M. Bradley Drummond, Diane Gold, Maciej Goniewicz, Eric R. Gross, Nadia N. Hansel, Philip K. Hopke, Robert A. Kloner, Vladimir B. Mikheev, Evan W. Neczypor, Kent Pinkerton, Lisa Postow, Irfan Rahman, Jonathan Samet, Matthias Salathe, Catherine Stoney, Philip Tsao, Rachel Widome, Tian Xia, DaLiao Xiao, Loren E. Wold. E-cigarette-induced Cardiovascular and Pulmonary Diseases. Circulation 2020
Manevski M, Muthumalage T, Devadoss D, Sundar IK, Wang Q, Singh KP, Unwalla HJ, Chand HS, Rahman I.Manevski M, Rahman I. Cellular stress responses and dysfunctional Mitochondrial-cellular senescence, and therapeutics in chronic respiratory diseases. Redox Biol. 2020 Jun;33:101443. doi: 10.1016/j.redox.2020.101443. Epub 2020 Jan 25.
Kaur G, Muthumalage T, Rahman I. Mechanisms of toxicity and biomarkers of flavoring and flavor enhancing chemicals in emerging tobacco and non-tobacco products. Toxicol Lett. 2018 May 15;288:143-155. doi: 10.1016/j.toxlet.2018.02.025. Epub 2018 Feb 23. Review. PMID: 29481849
Devadoss D, Long C, Langley RJ, Manevski M, Nair M, Campos MA, Borchert G, Rahman I, Chand HS. Long Noncoding Transcriptome in Chronic Obstructive Pulmonary Disease. Am J Respir Cell Mol Biol. 2019 Sep 5. doi: 10.1165/rcmb.2019-0184TR.PMID:31486667
Javed F, Kellesarian SV, Abduljabbar T, Abduljabbar AT, Akram Z, Vohra F, Rahman I, Romanos GE. Influence of involuntary cigarette smoke inhalation on osseointegration: a systematic review and meta-analysis of preclinical studies. Int J Oral Maxillofac Surg. 2017 Dec 9. pii: S0901-5027(17)31683-1. Doi 10.1016/j.ijom.2017.11.009. [Epub ahead of print] Review. PMID: 29233582
Isaac K. Sundar, Michael T. Sellix and Irfan Rahman. Redox Regulation of Molecular Clock in Chronic Airway Diseases. Free Rad Biol Med 2017.
Holger Behrsing1, Hans Raabe1, Raymond Tice2, Robert Devlin3, Kent Pinkerton4, Günter Oberdörster5, Chris Wright6, Roman Wieczorek7, Michaela Aufderheide8, Sandro Steiner9 Tobias Krebs10, Bahman Asgharian11, Richard Corley12, Michael Oldham13, Jason Adamson6, Xiang Li14, Irfan Rahman15, Sonia Grego16, Pei-Hsuan Chu17, Shaun McCullough18, Erin Hill1, Rodger Curren1. In Vitro Exposure Systems and Dosimetry Assessment Tools for Inhaled Tobacco Products: Workshop Proceedings, Conclusions, and Paths Forward for In Vitro Model Use. ATLA (Alternatives to Laboratory Animals). 2017
Fawad Javed, Sergio Varela Kellesarian, Isaac K. Sundar, Georgios E. Romanos, and Irfan Rahman.. Electronic-cigarette aerosol on periodontal and pulmonary tissues: effects on pro-fibrogenic and dysregulated repair responses. Oral Diseases 2017
F. Javed, I. Rahman, GE Romanos. Tobacco-product usage and success and survival of dental implants. J Perio2000 (Review), 2017
Fawad Javed, Shatha Subhi ALHarthi, Munerah Saleh BinShabaib, Sangeeta Gajendra, Georgios E. Romanos, Irfan Rahman Toxicological impact of waterpipe smoking and flavorings in the oral cavity and respiratory system. Inhalation Toxiology, 2017
Lerner CA, Sundar IK, Rahman I. Recent Insights into Mitochondrial Dynamics, Dysfunction, and Inflammation in Lung Diseases. Int. J. of Biochem. and Molec. Biol. 2016.
Sundar IK, Yao H, Sellix MT, Rahman I. Circadian Molecular Clock in Lung Pathophysiology. Am J Physiol Lung Cell Mol Physiol. 2015, PMID: 26361874
Isaac K. Sundar, Hongwei Yao, Michael T. Sellix, and Irfan Rahman. Circadian Clock Coupled Lung Cellular and Molecular Functions in Chronic Airway Diseases. Am J Respir Cell Mol Biol. 2015 Sep;53(3):285-90, PMID: 25938935
Jae-woong Hwang*, Samuel Caito*, Isaac K. Sundar*, Hongwei Yao, and Irfan Rahman. Redox regulation of SIRT1 in inflammation and senescence. Free Rad Biol Med 61C: 95-110, 2013. PMID 23542362
Yao H, Rahman I. Perspectives on translational and therapeutic aspects of SIRT1 in inflammaging and senescence. Biochem Pharmacol. 2012. PMID: 22796566. 84: 1332-9.
Yao H and Rahman I. Role of histone deacetylase 2 in epigenetics and cellular senescence: implications in lung inflammaging. Am J Physiol: Lung Cell Mol Physiol 2012. PMID: 22842217. 303:L557-66.
Sundar IK*, Yao, H, Rahman I. Oxidative stress and chromatin remodeling in COPD and smoking-related diseases. Antioxidant Redox Signaling, 2012. PMID: 22978694. 18: 1956-71, 2013. PMID: 22978694.
Rahman I, Kinnula VL. Strategies to decrease ongoing oxidant burdent in COPD. Exp Rev in Clin Pharmacol. 2012, 5 (3), 293-309. PMID 22697592
Rahman I, MacNee W. Antioxidant pharmacological therapies for COPD. Curr Opin Pharmacol 2012, 12: 256-65.
Yang SR, Rahman I, Trosko JE, Kang KS. Oxidative stress-induced biomarkers for stem cell-based chemical screening. Prev Med 2012, 54 Suppl:S42-9.
Rahman I. Pharmacological antioxidant strategies as therapeutic interventions for COPD. Biochimica et Biophysica Acta 2012, 1822(5): 714-28.
Rahman I, Kinnula VL, Gorbunova V, Yao H. SIRT1 as a therapeutic target in inflammaging of the pulmonary disease. Prev Med. 2012, 54 Suppl: S20-8.
Isaac K. Sundar * and Rahman I. Vitamin D, epigenetics, and susceptibility of chronic lung diseases. Frontiers in Pharmacology of Respiratory Diseases. 2011, 2: 50.
Yao H*, Rahman I. Current concepts on oxidative/carbonyl stress, inflammation and epigenetics in pathogenesis of chronic obstructive pulmonary disease, and therapeutic targets. Toxicol Appl Pharmacol. 2011, 254(2):72-85.
Sundar IK, Mullapudi N, Yao H, Spivack SD, Rahman I. Lung cancer and its association with chronic obstructive pulmonary disease: update on nexus of epigenetics. Curr Opin Pulm Med. 2011; 17: 279-85.
Sundar IK, Caito S, Yao H, Rahman I. Oxidative stress, thiol redox signaling methods in epigenetics. Methods Enzymol. (Academic Press) 2010; 474: 213-44.
Singh S, Vrishni S, Singh BK, Rahman I, Kakkar P. Nrf2-ARE stress response mechanism: a control point in oxidative stress-mediated dysfunctions and chronic inflammatory diseases. Free Radic Res. 44:1267-88; 2010.
Edirisinghe I*, Rahman I. Cigarette smoke-mediated oxidative stress, shear stress, and endothelial dysfunction: role of VEGFR2. Ann N Y Acad Sci. 1203:66-72; 2010.
Chung S*, Yao H*, Caito S*, Hwang JW*, Arunachalam G*, Rahman I. Regulation of SIRT1 in cellular functions: role of polyphenols. Arch Biochem Biophys. 501:79-90; 2010.
Rahman I, Chung S*,. Dietary polyphenols, deacetylases and chromatin remodeling in inflammation. World Rev Nutr Diet. 101:84-94. Epub 2010 Apr 30. PMID: 20436255/ J of Nutrigenetics and Nutrigenomics 3 (4-6): 220-231; 2010.
Rajendrasozhan S*, Yao H*,, Rahman I. Current perspectives on role of chromatin modifications and deacetylases in lung inflammation in COPD. J of COPD. 2009;6:291-7.
Yao H*,, Rahman I. Current concepts on the role of inflammation in COPD and lung cancer. Curr Opin Pharmacol. 9:375-83; 2009.
Biswas SK, Rahman I. Environmental toxicity, redox signaling and lung inflammation: the role of glutathione. Mol Aspects Med. 30(1-2):60-76; 2009.
Rahman I. Antioxidant therapeutic advances in COPD. Ther Adv Respir Dis. 2:351-374, 2008.
Louhelainen N, Myllarniemi M, Rahman I, Kinnula V. Airway biomarkers of oxidant burden in asthma and COPD: Current and Future Perspectives. Int J. COPD, 3:585-603, 2008.
Biswas SK and Rahman I. Modulation of steroid activity in chronic inflammation: a novel anti-inflammatory role for curcumin. Molecular Nutrition & Food Research, 52:987-994, 2008.
Rahman I. Dietary polyphenols mediated regulation of oxidative stress and chromatin remodeling in inflammation. Nutrition Reviews. 66:S42-S45, 2008.
Rajendrasozhan S*, Yang SR*, Edirisinghe I*, Yao H*, Adenuga D* and Rahman I. Deacetylases and NF-B in Redox Regulation of Cigarette Smoke Induced Lung Inflammation: Epigenetics in Pathogenesis of COPD. Antioxidant Redox Signaling, 10:799-811, 2008.
Yao H*, deBoer PI. Rahman I. Targeting lung inflammation: novel therapies for the treatment of COPD. Current Respiratory Medicine Reviews, 57-68, 2008.
Adenuga, D.*, and I. Rahman. Oxidative stress, histone deacetylase and corticosteroid resistance in severe asthma and COPD. Curr. Respir. Med. Rev. 3:57-68, 2007.
Yao, H.*, S. Yang*, A. Kode*, S. Rajendrasozhan*, S. Caito*, D. Adenuga*, R. Henry*, I. Edirisinghe*, and I. Rahman. Redox regulation of lung inflammation: role of NADPH oxidase and NF-kappaB signalling. Biochem. Soc. Transactions. 35(Pt 5):1151-5, 2007.
de Boer, W.I., H. Yao*, I. Rahman. Future therapeutic treatment of COPD: struggle between oxidants and cytokines. Int. J. COPD. 2(3):205-28, 2007.
Rahman, I., and I.M. Adcock. Oxidative stress and redox regulation of lung inflammation in COPD. Eur. Respir. J. 28:219-242, 2006.
Rahman, I., S.K. Biswas*, and P.A. Kirkham. Regulation of inflammation and redox signaling by dietary polyphenols. Biochem. Pharmacol. 72:1439-1452, 2006.
Rahman, I., and I. Kilty. Antioxidant Therapeutic Targets in COPD. Curr. Drug Targets. 7:707-720, 2006.
Kirkham, P., and I. Rahman. Oxidative stress in asthma and COPD. Antioxidants as therapeutic strategy. Pharmacol. Ther. 111:476-494, 2006.
Rahman, I., S.K. Biswas*, and A. Kode*. Oxidant and antioxidant balance in the airways and airway diseases. Eur. J. Pharmacol. 533:222-239, 2006.
Rahman, I. Beneficial effects of dietary polyphenols using lung inflammation as a model. J. Sci. Food Agric. 86:2499-2502, 2006.
Rahman, I., S.R. Yang*, and S. Biswas*. Current concepts of redox signaling in the lungs. Antioxid. Redox Signal. 8:681-689, 2006.
Rahman, I. Antixoidant therapies in COPD. Int. J. COPD. 1:15-29, 2006.
Biswas, S., A.S. Chida*, and I. Rahman. Redox modifications of protein-thiols: emerging roles in cell signaling. Biochem. Pharmacol. 71:551-564, 2006.
Rahman, I., S. Biswas, L.A. Jimenez, M. Torres, and H.J. Forman. Glutathione and redox signaling in the lungs. Antioxid. Redox Signal. 7:42-59, 2005.
Aruoma, O.I., K.S. Kang, T. Bahorun, M.K. Sung, and I. Rahman. Oxidative damage and chronic inflammation induced by smoking: potential antioxidant and peripheral biomarker considerations. Cancer Prevention Research. 10, 149-158, 2005.
Rahman, I. Oxidative stress in pathogenesis of chronic obstructive pulmonary disease: cellular and molecular mechanisms. Cell Biochem. Biophys. 43:167-88, 2005.
Rahman I. Oxidants, glutathione, and -glutamylcysteine synthetase in lung inflammation. Mutat. Res. 579:58-80, 2005.
Rahman, I. The role of oxidative stress in the pathogenesis of COPD: Implications for therapy. Treat. Respir. Med. 4:175-200, 2005.
Bhattacharya, K., I. Rahman, and Q. Rahman. Oxidative, inflammatory and genetic biomarkers in the risk assessment of fibers/particles exposure. Mutat. Res. 579:6-21, 2005.
Rahman, I., J.A. Marwick*, and P.A. Kirkham. Redox modulation of histone acetylation and deacetylation in vitro and in vivo: modulation of NF-B and pro-inflammatory genes. Biochem. Pharmacol. 68:1255-1267, 2004.
Rahman, I., and Biswas, S.K. Non-invasive biomarkers of oxidative stress: Reproducibility and methological issues. Redox Report. 9:125-143, 2004.
Rahman, I. Non-invasive biomarkers of oxidative stress and inflammation in breath condensate. Society for Free Radical Research-India Bulletin. 3:15-23, 2004.
Rahman, I. Oxidative stress, chromatin remodeling and gene transcription in inflammation and chronic lung disease. J. Biochem. Mol. Biol. 36: 95-109, 2003.
Rahman, I., and F. Kelly. Non-invasive biomarkers in breath condensate: A promising new approach in free radical research. Free Radic. Res. 37:1253-1266, 2003.
Rahman, I. Glutathione and glutamylcysteine ligase regulation by oxidative stress in lung inflammation. Biochemistry Biophysics Research Development: A web based journal. www.researchsignpost.com, 2003.
Donaldson, K., V. Stone, P. Gilmour, L.A. Jimenez, S. Faux, I. Rahman, and W. MacNee. The role of oxidative stress and calcium signaling by environmental particles. Free Radic. Biol. Med. 34:1369-1382, 2003.
Rahman, I., P. Gilmour, L.A. Jimenez, F. Antonicelli, and W. MacNee. Oxidative stress alters chromatin remodeling and activates NF-B in alveolar epithelial cells. International Prooceedings of the 11th Biennal Meeting of the SFRR International. 2003.
Rahman, I. Oxidative stress, transcription factors and chromatin remodeling in lung inflammation. Biochem. Pharmacol. 64:935-942, 2002.
Rahman, I. Oxidative stress and gene transcription in asthma and COPD: Antioxidant therapeutic targets. Curr. Drug Targets Inflamm. Allergy. 1:291-315, 2002.
MacNee, W., and I. Rahman. Is oxidative stress central to the pathogenesis of chronic obstructive pulmonary disease? Trends Mol. Med. 7:55-62, 2001.
Rahman, I., and W. MacNee. Regulation of redox glutathione levels and gene transcription in lung inflammation: therapeutic approaches. Free Radic. Biol. Med. 28:1405-1420, 2000.
Rahman, I., and W. MacNee. Oxidative stress and regulation of glutathione synthesis in lung inflammation. Eur. Respir. J. 16:534-554, 2000.
Rahman, I. Regulation of NF-B and AP-1 and glutathione synthesis by TNF- and dexamethasone in alveolar epithelial cells. Biochem. Pharmacol. 60:1041-1049, 2000.
Rahman, I., and W. MacNee. Lung glutathione and oxidative stress : Implications in cigarette smoke-induced airways disease. Am. J. Physiol. 277:L1067-L1088, 1999.
MacNee, W., and I. Rahman. Oxidants and antioxidant in COPD: Therapeutic targets. Am. J. Respir. Crit. Care Med. 160:S1-S8, 1999.
Rahman, I. Inflammation and regulation of glutathione in lung cells. Antioxid. Redox Signal. 1:425-447, 1999.
Rahman, I., and W. MacNee. Role of transcription factors in inflammatory lung diseases. Thorax. 53:601-612, 1998.
Rahman, I., and W. MacNee. Oxidant/antioxidant imbalance in smokers and in chronic obstructive pulmonary disease. Thorax. 51:348-350, 1996.
Rahman, I., and W. MacNee. Role of oxidants/antioxidants in smoking-induced airways diseases. Free Radic. Biol. Med. 21:669-681, 1996.
MacNee, W., and I. Rahman. Oxidants/antioxidants in idiopathic pulmonary fibrosis. Thorax. 50:S53-S58, 1995.
MacNee, W., and I. Rahman. Oxidants/antioxidants in idiopathic pulmonary fibrosis. Thorax. 50:S53-S58, 1995.
